Drug details:
Molecular formula: C₂₃H₁₈N₂O₉

Standard name: 5-[5-[(E)-3-[[(1S)-1-carboxy-2-(4-nitrophenyl)ethyl]amino]-3-oxoprop-1-enyl]furan-2-yl]-2-hydroxybenzoic acid

Curated SMILES: O=C(/C=C/C1=CC=C(C2=CC(C(=O)O)=C(O)C=C2)O1)NC(CC1=CC=C([N+](=O)[O-])C=C1)C(=O)O

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Leone M, et al., 2010. NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH. Chem Biol Drug Des 76(1):10-6.