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4,4'-Thiobis(3-Methylphenol)

Drug details:
Molecular formula: C14H14O2S

Classification: Aryl thioethers; Thioethers; Organosulfur compounds; Organic compounds;
Synonyms:  4-(4-hydroxy-2-methylphenyl)sulfanyl-3-methylphenol
4-hydroxy-2-methylphenyl sulphide

Chemical structure:
Depiction based on curated SMILES S HO CH 3 H 3 C OH

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Inhibits translocation of Yop effectors.
Max phase: Preclinical (in vitro)
Publication:
Pan NJ, et al., 2009. Targeting type III secretion in Yersinia pestis. Antimicrob Agents Chemother 53(2):385-92.








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