Drug details:
Molecular formula: C₃₁H₂₅N₅O₅S

Standard name: 6-hydroxy-3-[1-[5-oxo-5-[(4-phenyl-1,3-thiazol-2-yl)amino]pentyl]triazol-4-yl]-2-phenyl-1-benzofuran-5-carboxylic acid

Curated SMILES: C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)CCCCN3C=C(N=N3)C4=C(OC5=CC(=C(C=C54)C(=O)O)O)C6=CC=CC=C6

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Huang Z, et al., 2010. Derivatives of salicylic acid as inhibitors of YopH in Yersinia pestis. Chem Biol Drug Des 76(2):85-99.