Drug details:
Molecular formula: C₂₇H₂₂N₄O₅

Standard name: 3-[1-[3-(benzylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid

Curated SMILES: O=C(CCN1C=C(C2=C(C3=CC=CC=C3)OC3=C2C=C(C(=O)O)C(O)=C3)N=N1)NCC1=CC=CC=C1

Evidence for compound's anti-virulence activity:

Yersinia
Related VF: TTSS secreted effectors
Target: YopH
Drug effect: Targets the phosphotyrosine-binding pocket of YopH.
Max phase: Preclinical (in vitro)
Publication:
Huang Z, et al., 2010. Derivatives of salicylic acid as inhibitors of YopH in Yersinia pestis. Chem Biol Drug Des 76(2):85-99.