Drug details:
Molecular formula: C₂₇H₂₇LiN₂O₄S

Standard name: lithium;(3R)-8-cyclopropyl-6-(morpholin-4-ylmethyl)-7-(naphthalen-1-ylmethyl)-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylate

Curated SMILES: [Li+].[O-]C(=O)[C@H]1CSC2=C(C3CC3)C(CC3=CC=CC4=C3C=CC=C4)=C(CN3CCOCC3)C(=O)N21

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Type 1 fimbriae; P fimbriae
Target: PapD
Drug effect: Blocking chaperone and usher functions.
Max phase: Preclinical (in vivo)
Publication:
Pinkner JS, et al., 2006. Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A 103(47):17897-902.