Escherichia
Related VF: Heat-labile toxin (LT)
Target: EltB
Drug effect: Pore-binding ligand for AB5 toxins.
Max phase: Preclinical (in vivo)
Publication: Hovey BT, et al., 1999. Structure-based discovery of a pore-binding ligand: towards assembly inhibitors for cholera and related AB5 toxins. J Mol Biol 285(3):1169-78.