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3-Methylthio-1,4-diphenyl-1H-1,3,4-triazolium

Drug details:
Molecular formula: C15H14N3S+

Classification: Triazoles; Azoles; Organoheterocyclic compounds; Organic compounds;
Synonym:  3-methylsulfanyl-1,4-diphenyl-1,2,4-triazol-4-ium

Chemical structure:
Depiction based on curated SMILES N H 3 C + N N S

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Heat-labile toxin (LT)
Target: EltB
Drug effect: Pore-binding ligand for AB5 toxins.
Max phase: Preclinical (in vivo)
Publication:
Hovey BT, et al., 1999. Structure-based discovery of a pore-binding ligand: towards assembly inhibitors for cholera and related AB5 toxins. J Mol Biol 285(3):1169-78.








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