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methyl 3-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzoate

Drug details:
Molecular formula: C20H22O8

Classification: Carbohydrates and carbohydrate conjugates; Organooxygen compounds; Organic oxygen compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES OH OH HO HO H 3 C O O O O

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Bound to the FimH lectin domain to interfere with bacterial adhesion, invasion and biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Cusumano CK, et al., 2011. Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med 3(109):109ra115.








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