Drug details:
Molecular formula: C₂₃H₂₅F₃N₂O₈

Standard name: 1-N,3-N-dimethyl-5-[3-(trifluoromethyl)-4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]benzene-1,3-dicarboxamide

Curated SMILES: CNC(=O)C1=CC(C(=O)NC)=CC(C2=CC(C(F)(F)F)=C(OC3OC(CO)C(O)C(O)C3O)C=C2)=C1

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Bound to the FimH lectin domain to interfere with bacterial adhesion, invasion and biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Cusumano CK, et al., 2011. Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci Transl Med 3(109):109ra115.