Drug details:
Molecular formula: C₂₃H₂₆N₂O₆

Standard name: (2R,3S,4S,5S,6R)-2-[(R)-[4-(1-aminoisoquinolin-7-yl)-2-methylphenyl]-hydroxymethyl]-6-(hydroxymethyl)oxane-3,4,5-triol

Curated SMILES: CC1=CC(C2=CC=C3C=CN=C(N)C3=C2)=CC=C1[C@@H](O)C1OC(CO)C(O)C(O)C1O

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: Type 1 fimbriae
Target: FimH
Drug effect: Bound to the FimH lectin domain to interfere with bacterial adhesion, invasion and biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Mydock-McGrane L, et al., 2016. Antivirulence C-Mannosides as Antibiotic-Sparing, Oral Therapeutics for Urinary Tract Infections. J Med Chem 59(20):9390-9408.