Drug details:
Molecular formula: C₂₀H₃₈N₈O₇

Standard name: 2-[2-[[2,3-diamino-8-(2-amino-1-carbamoyl-4,5-dihydroimidazol-4-yl)-6,7-dihydroxyoctanoyl]amino]propanoylamino]-3-methylbutanoic acid

Curated SMILES: CC(C)C(C(=O)O)NC(=O)C(C)NC(=O)C(C(CCC(C(CC1CN(C(=N1)N)C(=O)N)O)O)N)N

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Markedly inhibit EPEC-induced hemolysis.
Max phase: Preclinical (in vitro)
Publication:
Iwatsuki M, et al., 2008. Guadinomines, Type III secretion system inhibitors, produced by Streptomyces sp. K01-0509. I: taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo) 61(4):222-9.