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Guadinomic acid

Drug details:
Molecular formula: C10H18N4O4

Classification: Fatty acids and conjugates; Fatty Acyls; Lipids and lipid-like molecules; Organic compounds;
Chemical structure:
Depiction based on curated SMILES OH HO O H NH 2 NH 2 O N N H

Evidence for compound's anti-virulence activity:

Escherichia
Related VF: TTSS (Type III secretion system)
Target: Not determined
Drug effect: Markedly inhibit EPEC-induced hemolysis.
Max phase: Preclinical (in vitro)
Publication:
Iwatsuki M, et al., 2008. Guadinomines, Type III secretion system inhibitors, produced by Streptomyces sp. K01-0509. I: taxonomy, fermentation, isolation and biological properties. J Antibiot (Tokyo) 61(4):222-9.








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