Drug details:
Molecular formula: C₂₁H₁₈O₅

Standard name: 4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one

Synonyms:

4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one 4-(4-phenoxybutoxy)furo[3,2-g]chromen-7-one 7H-Furo[3,2-g][1]benzopyran-7-one, 4-(4-phenoxybutoxy)- 7H-Furo(3,2-g)(1)benzopyran-7-one, 4-(4-phenoxybutoxy)- 5-(4-Phenoxybutoxy)psoralen 4-(4-Phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one 5-(4-phenoxybutoxy) psoralen 4-[4-(phenoxy)butoxy]furo[3,2-g]chromen-7-one 5-(4-Phenoxybutoxy)psoralen, >=98% (HPLC), solid 4-(4-Phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-on

Curated SMILES: C1=CC=C(C=C1)OCCCCOC2=C3C=CC(=O)OC3=CC4=C2C=CO4

Evidence for compound's anti-virulence activity:

Coxiella
Related VF: Dot/Icm T4SS
Target: Not determined
Drug effect: Interferes with cargo delivery by the T4SS.
Max phase: Preclinical (in vitro)
Publication:
Cheng E, et al., 2022. A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System. mBio 13(2):e0024022.

Legionella
Related VF: Dot/Icm (Defect in organella trafficking/intracellular multiplication)
Target: Not determined
Drug effect: Interferes with cargo delivery by the T4SS.
Max phase: Preclinical (in vitro)
Publication:
Cheng E, et al., 2022. A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System. mBio 13(2):e0024022.