Drug details:
Molecular formula: C₁₀H₁₄O

Standard name: 2-methyl-5-propan-2-ylphenol

Synonyms:

5-Isopropyl-2-methylphenol Isopropyl-o-cresol Antioxine 2-p-Cymenol 5-Isopropyl-o-cresol o-Thymol Isothymol Karvakrol 2-Hydroxy-p-cymene ......

Curated SMILES: CC1=C(C=C(C=C1)C(C)C)O

Evidence for compound's anti-virulence activity:

Aeromonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits protease production, hemolytic activity, EPS production, and biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Wang J, et al., 2022. Antimicrobial and Antivirulence Activities of Carvacrol against Pathogenic Aeromonas hydrophila. Microorganisms 10(11):2170.

Enterococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Biofilm eradication.
Max phase: Preclinical (in vitro)
Publication:
Miladi H, et al., 2017. Synergistic effect of eugenol, carvacrol, thymol, p-cymene and gamma-terpinene on inhibition of drug resistance and biofilm formation of oral bacteria. Microb Pathog 112:156-163.