Drug details:
Molecular formula: C₃₀H₄₈O₅

Standard name: (1S,2R,4aS,6aR,6aS,6bR,8aR,9R,10R,11R,12aR,14bS)-10,11-dihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid

Synonyms:

Dammarolic acid Asiantic acid (2alpha,3beta)-2,3,23-trihydroxyurs-12-en-28-oic acid Asiaticacid Urs-12en-28-oic acid, 2,3,23-trihydroxy-, (2alpha, 3beta, 4alpha)- 2,3,23-trihydroxyurs-12-en-28-oic acid Esculentic acid (Diplazium) 2alpha,23-Dihydroxyursolic acid Urs-12-en-28-oic acid, 2,3,23-trihydroxy-, (2a,3b,4a)- ......

Curated SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O

Evidence for compound's anti-virulence activity:

Enterococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Wojnicz D, et al., 2017. Anti-enterococcal activities of pentacyclic triterpenes. Adv Clin Exp Med 26(3):483-490.