Drug details:
Molecular formula: C₁₄H₁₂O₃

Standard name: 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol

Synonyms:

trans-resveratrol 3,4',5-Trihydroxystilbene (E)-5-(4-Hydroxystyryl)benzene-1,3-diol 3,5,4'-Trihydroxystilbene (E)-resveratrol Resvida 3,4',5-Stilbenetriol 5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol 3,4',5-Trihydroxy-trans-stilbene ......

Curated SMILES: C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O

Evidence for compound's anti-virulence activity:

Aeromonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits quorum sensing-mediated aerolysin production and biofilm.
Max phase: Preclinical (in vitro)
Publication:
Santos CA, et al., 2021. Exploring Phenolic Compounds as Quorum Sensing Inhibitors in Foodborne Bacteria. Front Microbiol 12:735931.

Helicobacter
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Reduces the biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Di Fermo P, et al., 2020. Searching for New Tools to Counteract the Helicobacter pylori Resistance: The Positive Action of Resveratrol Derivatives. Antibiotics (Basel) 9(12):891.

Staphylococcus
Related VF: α-hemolysin
Target: Not determined
Drug effect: Decreases the expression of hla and reduces alpha-toxin production in Staphylococcus aureus isolates by downregulating saeRS.
Max phase: Preclinical (in vivo)
Publication:
Duan J, et al., 2018. Subinhibitory concentrations of resveratrol reduce alpha-hemolysin production in Staphylococcus aureus isolates by downregulating saeRS. Emerg Microbes Infect 7(1):136.