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3-(2,4-dichloroanilino)-N-hydroxypropanamide

Drug details:
Molecular formula: C9H10Cl2N2O2

Classification: Amino acids, peptides, and analogues; Carboxylic acids and derivatives; Organic acids and derivatives; Organic compounds;
Chemical structure:
Depiction based on curated SMILES Cl Cl N H O NH HO

Evidence for compound's anti-virulence activity:

Helicobacter
Related VF: Urease
Target: Urease
Drug effect: Exhibits significant anti-urease potential.
Max phase: Preclinical (in vivo)
Publication:
Liu Q, et al., 2018. Arylamino containing hydroxamic acids as potent urease inhibitors for the treatment of Helicobacter pylori infection. Eur J Med Chem 156:126-136.








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