Drug details:
Molecular formula: C₅H₅N₅O

Standard name: N-(7H-purin-6-yl)hydroxylamine

Synonyms:

N-(7H-purin-6-yl)hydroxylamine 6-Hydroxyaminopurine N-Hydroxyadenine 6-Hydroxylaminopurine N(6)-Hydroxyadenine N-Hydroxy-1H-purin-6-amine ADENINE, N-HYDROXY- 1H-Purin-6-amine, N-hydroxy- N-Hydroxy-1H-adenine ......

Curated SMILES: C1=NC2=C(N1)C(=NC=N2)NO

Evidence for compound's anti-virulence activity:

Listeria
Related VFcategory: Regulation
Target: Not determined
Drug effect: Decreases virulence gene expression by reducing both the levels and activity of the virulence regulator PrfA.
Max phase: Preclinical (in vitro)
Publication:
Krajewski SS, et al., 2017. Antibacterial and antivirulence effect of 6-N-hydroxylaminopurine in Listeria monocytogenes. Nucleic Acids Res 45(4):1914-1924.