Drug details:
Molecular formula: C₁₉H₂₂N₂O₃S

Standard name: 8-(dimethylamino)-7-[(2,3-dimethylphenyl)methyl]-5-oxo-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid

Curated SMILES: C1C=C(C(C)=C(C=1)CC(=CC(=O)N1C2C(O)=O)C(=C1SC2)N(C)C)C

Evidence for compound's anti-virulence activity:

Listeria
Related VF: PrfA (Pleiotropic regulatory factor)
Target: PrfA
Drug effect: Binds to PrfA, the master virulence regulator to decrease virulence factor expression.
Max phase: Preclinical (in vitro)
Publication:
Kulén M, et al., 2018. Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J Med Chem 61(9):4165-4175.