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Naringenin

Drug details:
Molecular formula: C15H12O5

Classification: Flavans; Flavonoids; Phenylpropanoids and polyketides; Organic compounds;
Synonyms:  (S)-Naringenin
salipurpol
Naringenine
Salipurol
(S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
(2S)-Naringenin
pelargidanon
naringetol
Asahina
......

Chemical structure:
Depiction based on curated SMILES O HO OH OH O

Evidence for compound's anti-virulence activity:

Listeria
Related VF: LLO (Listeriolysin O)
Target: Hly
Drug effect: Inhibits the activity of LLO.
Max phase: Preclinical (in vitro)
Publication:
Wang J, et al., 2015. Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling. Sci Rep 5:8864.








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