Drug details:
Molecular formula: C₂₀H₃₉ClN₄O

Standard name: 4-(2-amino-1H-imidazol-5-yl)-N-tridecylbutanamide;hydrochloride

Curated SMILES: CCCCCCCCCCCCNC(=O)CCCC1=CN=C(N1)N.Cl

Evidence for compound's anti-virulence activity:

Acinetobacter
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Ballard TE, et al., 2008. Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship study. Chemistry 14(34):10745-61.

Pseudomonas
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation.
Max phase: Preclinical (in vitro)
Publication:
Ballard TE, et al., 2008. Synthesis and antibiofilm activity of a second-generation reverse-amide oroidin library: a structure-activity relationship study. Chemistry 14(34):10745-61.

Staphylococcus
Related VFcategory: Regulation
Target: VicR
Drug effect: Inhibits biofilm formation via binding to VicR, a key response regulator.
Max phase: Preclinical (in vivo)
Publication:
Liu C, et al., 2023. Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator. mBio 14(3):e0013723.