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3-(3,4,5-trimethoxyphenyl)propyl 1-[(4-nitrophenyl)methylsulfonyl]piperidine-2-carboxylate

Drug details:
Molecular formula: C25H32N2O9S

Classification: Amino acids, peptides, and analogues; Carboxylic acids and derivatives; Organic acids and derivatives; Organic compounds;
Chemical structure:
Depiction based on curated SMILES N S O O + N O _ O CH 3 O O H 3 C O CH 3 O O

Evidence for compound's anti-virulence activity:

Neisseria
Related VFcategory: Others
Target: MIP
Drug effect: Inhibits the adherence, invasion and/or survival of N. meningitidis in epithelial cells.
Max phase: Preclinical (in vitro)
Publication:
Reimer A, et al., 2016. Inhibitors of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity. Int J Antimicrob Agents 48(4):401-8.








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