Drug details:
Molecular formula: C₂₁H₂₀O₁₀

Standard name: 5-hydroxy-3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one

Synonyms:

Genistine Genistoside Genistein 7-glucoside Genisteol 7-monoglucoside Glucosyl-7-genistein Genistein 7-O-beta-D-glucoside genistein 7-O-glucoside Genistein, 7-O-beta-D-glucoside 4',5,7-trihydroxyisoflavone 7-D-glucoside ......

Curated SMILES: C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O

Evidence for compound's anti-virulence activity:

Listeria
Related VF: LLO (Listeriolysin O)
Target: Hly
Drug effect: Inhibits the peptidase activity of SrtA and the hemolytic activity of LLO.
Max phase: Preclinical (in vivo)
Publication:
Liu M, et al., 2023. Isoflavone glucoside genistin, an inhibitor targeting Sortase A and Listeriolysin O, attenuates the virulence of Listeria monocytogenes in vivo and in vitro. Biochem Pharmacol 209:115447.