Drug details:
Molecular formula: C₉H₁₅I₂NO

Standard name: 5,7-diiodo-1,2,3,4,4a,5,6,7,8,8a-decahydroquinolin-8-ol

Curated SMILES: OC1C(I)CC(I)C2CCCNC12

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.