Drug details:
Molecular formula: C₁₅H₁₄BrNO₄

Standard name: diethyl 6-bromoquinoline-2,4-dicarboxylate

Curated SMILES: CCOC(=O)C1=CC(=NC2=C1C=C(C=C2)Br)C(=O)OCC

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.