Drug details:
Molecular formula: C₈H₆N₂S₄

Standard name: (2-ethylsulfanyl-5-thiocyanatothiophen-3-yl) thiocyanate

Curated SMILES: CCSC1=C(SC#N)C=C(SC#N)S1

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.