Drug details:
Molecular formula: C₁₂H₁₂N₄S

Standard name: 2-cyano-N'-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)ethanimidamide

Curated SMILES: N#CC/C(N)=N/C1=C(C#N)C2=C(CCCC2)S1

Evidence for compound's anti-virulence activity:

Brucella
Related VF: VirB type IV secretion system
Target: VirB8
Drug effect: Inhibits T4SS by targeting an essential assembly protein VirB8.
Max phase: Preclinical (in vivo)
Publication:
Paschos A, et al., 2011. An in vivo high-throughput screening approach targeting the type IV secretion system component VirB8 identified inhibitors of Brucella abortus 2308 proliferation. Infect Immun 79(3):1033-43.