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[2-(4-acetylanilino)-2-oxoethyl]phosphonic acid

Drug details:
Molecular formula: C10H12NO5P

Classification: Carbonyl compounds; Organooxygen compounds; Organic oxygen compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES _ O _ O O P O CH 3 N H O

Evidence for compound's anti-virulence activity:

Bacillus
Related VF: Collagenase
Target: ColQ1
Drug effect: Binds to bacterial collagenase to inhibit their activity thus to reduce cytotoxicity to host cells.
Max phase: Preclinical (in vivo)
Publication:
Alhayek A, et al., 2022. Inhibition of Collagenase Q1 of Bacillus cereus as a Novel Antivirulence Strategy for the Treatment of Skin-Wound Infections. Adv Ther (Weinh) 5(3):2100222.








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