Drug details:
Molecular formula: C₁₁H₂₀O₂

Standard name: undec-10-enoic acid

Synonyms:

10-UNDECENOIC ACID Undec-10-enoic acid Undecenoic acid Desenex 10-Hendecenoic acid Renselin Sevinon Declid 10-Undecylenic acid ......

Curated SMILES: C=CCCCCCCCCC(=O)O

Evidence for compound's anti-virulence activity:

Bacillus
Related VFcategory: Biofilm
Target: LuxS/AI-2
Drug effect: Inhibits LuxS/AI-2 QS system to counteract bacterial pathogenicity and virulence.
Max phase: Preclinical (in vitro)
Publication:
Fernandes S, et al., 2023. Curcumin and 10-undecenoic acid as natural quorum sensing inhibitors of LuxS/AI-2 of Bacillus subtilis and LasI/LasR of Pseudomonas aeruginosa. Food Res Int 165:112519.

Pseudomonas
Related VF: Quorum sensing
Target: LasI
Drug effect: Inhibits QS system to counteract bacterial pathogenicity and virulence.
Max phase: Preclinical (in vitro)
Publication:
Fernandes S, et al., 2023. Curcumin and 10-undecenoic acid as natural quorum sensing inhibitors of LuxS/AI-2 of Bacillus subtilis and LasI/LasR of Pseudomonas aeruginosa. Food Res Int 165:112519.