Drug details:
Molecular formula: C₂₁H₂₈N₂O

Standard name: 1-(azepan-1-yl)-3-(N-phenylanilino)propan-2-ol

Synonyms:

1-(azepan-1-yl)-3-(N-phenylanilino)propan-2-ol 1-(azepan-1-yl)-3-(diphenylamino)propan-2-ol

Curated SMILES: OC(CN1CCCCCC1)CN(C1=CC=CC=C1)C1=CC=CC=C1

Evidence for compound's anti-virulence activity:

Bacillus
Related VFcategory: Nutritional/Metabolic factor
Target: KtrAB
Drug effect: Inhibits KtrAB ion channel complex, a component of the K+ homeostasis machinery to interfere with pathogen survival in host cells.
Max phase: Preclinical (in vitro)
Publication:
Fernandes AS, et al., 2021. Fluorometric Liposome Screen for Inhibitors of a Physiologically Important Bacterial Ion Channel. Front Microbiol 12:603700.