Drug details:
Molecular formula: C₅H₁₂NO₅P

Standard name: 3-[acetyl(hydroxy)amino]propylphosphonic acid

Synonyms:

{3-[acetyl(hydroxy)amino]propyl}phosphonic acid 3-[acetyl(hydroxy)amino]propylphosphonic acid FR900098 [3-(N-hydroxyacetamido)propyl]phosphonic acid 3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid Phosphonic acid, (3-(acetylhydroxyamino)propyl)- (3-(N-hydroxyacetamido)propyl)phosphonic acid 3-[ethanoyl(Hydroxy)amino]propylphosphonic Acid 3-(N-hydroxyacetamido)propylphosphonic acid ......

Curated SMILES: CC(=O)N(CCCP(=O)(O)O)O

Evidence for compound's anti-virulence activity:

Burkholderia
Related VFcategory: Motility
Target: Not determined
Drug effect: Reduces the mortality, and potentiates the biofilm inhibiting effect of ceftazidime.
Max phase: Preclinical (in vivo)
Publication:
Bove M, et al., 2022. The anti-virulence activity of the non-mevalonate pathway inhibitor FR900098 towards Burkholderia cenocepacia is maintained during experimental evolution. Microbiology (Reading) 168(3):10.1099/mic.0.001170.