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N-[(Z)-(2-hydroxy-3-prop-2-enylphenyl)methylideneamino]-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide

Drug details:
Molecular formula: C18H20N4O2

Classification: Amino acids, peptides, and analogues; Carboxylic acids and derivatives; Organic acids and derivatives; Organic compounds;
Chemical structure:
Depiction based on curated SMILES N H N CH 2 O N H N HO

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Motility
Target: Not determined
Drug effect: Inhibits sliding motility and then results in a decrease in bacterial virulence.
Max phase: Preclinical (in vitro)
Publication:
Ouertatani-Sakouhi H, et al., 2017. Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model. PLoS One 12(7):e0181121.








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