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S-(2,4-difluorophenyl) 2-[5-[4-(trifluoromethyl)phenyl]tetrazol-2-yl]ethanethioate

Drug details:
Molecular formula: C16H9F5N4OS

Classification: Tetrazoles; Azoles; Organoheterocyclic compounds; Organic compounds;
Chemical structure:
Depiction based on curated SMILES O F F F F F S N N N N

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Motility
Target: Not determined
Drug effect: Inhibits sliding motility and then results in a decrease in bacterial virulence.
Max phase: Preclinical (in vitro)
Publication:
Ouertatani-Sakouhi H, et al., 2017. Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model. PLoS One 12(7):e0181121.








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