Drug details:
Molecular formula: C₁₃H₁₇ClNO₆S₄⁺

Standard name: 3-[5-chloro-2-(3-sulfopropylsulfanyl)-1,3-benzothiazol-3-ium-3-yl]propane-1-sulfonic acid

Curated SMILES: C1=CC2=C(C=C1Cl)[N+](=C(S2)SCCCS(=O)(=O)O)CCCS(=O)(=O)O

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: Zmp1
Drug effect: Inhibits the Mycobacterium tuberculosis extracellular zinc metalloprotease 1 (Zmp1) that is essential for phagosome maturation and bacterial intracellular survival.
Max phase: Preclinical (in vitro)
Publication:
Mori M, et al., 2014. Discovery of the first potent and selective Mycobacterium tuberculosis Zmp1 inhibitor. Bioorg Med Chem Lett 24(11):2508-11.