Drug details:
Molecular formula: C₂₉H₂₃NO₄S

Standard name: 3-benzyl-2-methyl-1-(4-phenylbenzoyl)indole-5-sulfonic acid

Synonym:

3-Benzyl-1-(biphenyl-4-carbonyl)-2-methyl-1H-indole-5-sulfonic acid

Curated SMILES: CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)C4=CC=CC=C4)C=CC(=C2)S(=O)(=O)O)CC5=CC=CC=C5

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.