Drug details:
Classification: Sulfonated stilbenes; Stilbenes; Phenylpropanoids and polyketides; Organic compounds;

Curated SMILES: CC1=C(CC2=CC=CC=C2)C3=CC(=CC=C3N1C(=O)C4=CC=CS4)S(=O)(=O)O

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpB
Drug effect: Inhibits protein tyrosine phosphatase B (PtpB) to interfere with signal transduction pathways in macrophages.
Max phase: Preclinical (in vitro)
Publication:
Nören-Müller A, et al., 2006. Discovery of protein phosphatase inhibitor classes by biology-oriented synthesis. Proc Natl Acad Sci U S A 103(28):10606-11.