Drug details:
Molecular formula: C₂₀H₂₀ClN₃O₃S

Standard name: N-(5-chloro-2-methoxyphenyl)-2-(7-methyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-3-yl)acetamide

Curated SMILES: COC1=CC=C(Cl)C=C1NC(=O)CN1C=NC2=C(C1=O)C1=C(CC(C)CC1)S2

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Immune modulation
Target: CdnP
Drug effect: Inhibits bacterial phosphodiesterase (PDE) CdnP activity that responsible for cleaving bacterial c-di-AMP as well as host-derived cGAMP to blunt the host's response to infection.
Max phase: Preclinical (in vitro)
Publication:
Karanja CW, et al., 2021. Identification of a Mycobacterium tuberculosis Cyclic Dinucleotide Phosphodiesterase Inhibitor. ACS Infect Dis 7(2):309-317.