Drug details:
Molecular formula: C₁₃H₁₃NO₂

Standard name: 4-(2,5-dimethylpyrrol-1-yl)benzoic acid

Synonyms:

4-(2,5-dimethylpyrrol-1-yl)benzoic acid 4-(2,5-Dimethyl-pyrrol-1-yl)-benzoic acid 4-(2,5-Dimethyl-1H-pyrrol-1-yl)benzene-carboxylic acid Benzoic acid, 4-(2,5-dimethyl-1H-pyrrol-1-yl)- 4-(2,5-dimethyl-1-pyrrolyl)benzoic acid Benzoic acid,4-(2,5-dimethyl-1H-pyrrol-1-yl)- 4-(2,5-dimethyl-1H-pyrrol-1-yl)benzenecarboxylic acid p-(2,5-Dimethyl-1-pyrryl)benzoic acid N-(4-Carboxy)phenyl-2,5-dimethylpyrrole pyrrole, 1-(4-carboxy)phenyl-2,5-dimethyl-

Curated SMILES: CC1=CC=C(N1C2=CC=C(C=C2)C(=O)O)C

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpA
Drug effect: Inhibits protein tyrosine phosphatase PtpA to disrupt phagosome acidification and maturation.
Max phase: Preclinical (in vitro)
Publication:
Manger M, et al., 2005. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 6(10):1749-53.