Drug details:
Molecular formula: C₁₃H₁₃NO₃

Standard name: 4-(2,5-dimethylpyrrol-1-yl)-3-hydroxybenzoic acid

Synonyms:

4-(2,5-dimethylpyrrol-1-yl)-3-hydroxybenzoic acid 4-(2,5-dimethylpyrrol-1-yl)-3-hydroxy-benzoic acid

Curated SMILES: CC1=CC=C(N1C2=C(C=C(C=C2)C(=O)O)O)C

Evidence for compound's anti-virulence activity:

Mycobacterium
Related VFcategory: Exoenzyme
Target: PtpA
Drug effect: Inhibits protein tyrosine phosphatase PtpA to disrupt phagosome acidification and maturation.
Max phase: Preclinical (in vitro)
Publication:
Manger M, et al., 2005. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach. Chembiochem 6(10):1749-53.