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[(2S)-6-azaniumyl-1-[3-[3-[[(2S)-2,6-bis(azaniumyl)hexanoyl]amino]propyl-[(E)-octadec-9-enoyl]amino]propylamino]-1-oxohexan-2-yl]azanium

Drug details:
Molecular formula: C36H77N7O3+4

Classification: Amino acids, peptides, and analogues; Carboxylic acids and derivatives; Organic acids and derivatives; Organic compounds;
Chemical structure:
Depiction based on curated SMILES O + N H H H + N H H H N H H + N H H H + N H H H CH 3 O N N H O H

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Biofilm
Target: Not determined
Drug effect: Inhibits biofilm formation (membrane disruption might be a possible mechanism).
Max phase: Preclinical (in vitro)
Publication:
Konai MM, et al., 2015. Lysine-Based Small Molecules That Disrupt Biofilms and Kill both Actively Growing Planktonic and Nondividing Stationary Phase Bacteria. ACS Infect Dis 1(10):469-78.








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