Home
Search
Category
Compounds
Status
Download
Contacts
Resources



Solonamide B

Drug details:
Molecular formula: C32H50N4O6

Classification: Depsipeptides; Peptidomimetics; Organic acids and derivatives; Organic compounds;
Chemical structure:
Depiction based on curated SMILES CH 3 O NH H O O H 3 C CH 3 H 3 C CH 3 H H O HN H 3 C O HN H O N H H

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VF: δ-hemolysin
Target: Not determined
Drug effect: An agr quorum sensing inhibitor impedes δ-toxin production .
Max phase: Preclinical (in vivo)
Publication:
Baldry M, et al., 2018. Application of an agr-Specific Antivirulence Compound as Therapy for Staphylococcus aureus-Induced Inflammatory Skin Disease. J Infect Dis 218(6):1009-1013.








Back to Top
Back to Top
2004-2024 NIPB, CAMS&PUMC