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4-(2-amino-1H-imidazol-5-yl)-N-undecylbutanamide;hydrochloride

Drug details:
Molecular formula: C18H35ClN4O

Classification: Fatty amides; Fatty Acyls; Lipids and lipid-like molecules; Organic compounds;
Chemical structure:
Depiction based on curated SMILES ClH NH 2 NH N O H 3 C N H

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Regulation
Target: VicR
Drug effect: Inhibits biofilm formation via binding to VicR, a key response regulator.
Max phase: Preclinical (in vivo)
Publication:
Liu C, et al., 2023. Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator. mBio 14(3):e0013723.








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