Drug details:
Molecular formula: C₂₆H₄₄O₉

Standard name: 9-[(E)-4-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[[(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl]methyl]oxan-2-yl]-3-methylbut-2-enoyl]oxynonanoic acid

Synonyms:

Pseudomonic acid Bactroban Mupirocine Centany Pseudomonic acid A Bactoderm Mupirocina Mupirocinum Turixin ......

Curated SMILES: C[C@H]([C@H]1[C@@H](O1)C[C@H]2CO[C@H]([C@@H]([C@@H]2O)O)C/C(=C/C(=O)OCCCCCCCCC(=O)O)/C)[C@H](C)O

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VF: α-hemolysin
Target: Not determined
Drug effect: Inhibits α-toxin experession by down-regulating agr, saeRS and sarA.
Max phase: Preclinical (in vitro)
Publication:
Jin Y, et al., 2018. Sub-Inhibitory Concentrations of Mupirocin Strongly Inhibit Alpha-Toxin Production in High-Level Mupirocin-Resistant MRSA by Down-Regulating agr, saeRS, and sarA. Front Microbiol 9:993.