Drug details:
Molecular formula: C₁₅H₁₁ClO₆

Standard name: 2-(3,4-dihydroxyphenyl)chromenylium-3,5,7-triol;chloride

Synonyms:

Cyanidol chloride 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxychromenylium chloride Gastrotelos Cyanidin (Chloride) 1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, chloride EINECS 208-438-6 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-benzopyrylium chloride 3,3',4',5,7-Pentahydroxyflavylium chloride 3,3'4',5,7-Pentahydroxyflavylium chloride ......

Curated SMILES: C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2O)O)O)O)O.[Cl-]

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Others; Adherence; Biofilm
Target: SrtA
Drug effect: Inhibits SrtA activity and SrtA-related virulence phenotypes including fibrinogen adhesion, biofilm formation and surface protein (SpA) anchoring.
Max phase: Preclinical (in vivo)
Publication:
Su X, et al., 2022. Cyanidin chloride protects mice from methicillin-resistant Staphylococcus aureus-induced pneumonia by targeting Sortase A. Virulence 13(1):1434-1445.