Drug details:
Molecular formula: C₁₅H₁₂O₇

Standard name: (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydrochromen-4-one

Synonyms:

(+)-Taxifolin dihydroquercetin Distylin Taxifoliol (2R,3R)-Dihydroquercetin (+)-Dihydroquercetin Lavitol (+/-)-Taxifolin Diquertin ......

Curated SMILES: C1=CC(=C(C=C1[C@@H]2[C@H](C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Others; Adherence; Biofilm
Target: SrtA
Drug effect: Inhibits SrtA activity and SrtA-related virulence phenotypes including the adherence, biofilm formation and surface protein (SpA) anchoring.
Max phase: Preclinical (in vivo)
Publication:
Wang L, et al., 2021. Taxifolin, an Inhibitor of Sortase A, Interferes With the Adhesion of Methicillin-Resistant Staphylococcal aureus. Front Microbiol 12:686864.