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Quercitrin

Drug details:
Molecular formula: C21H20O11

Classification: Flavonoid glycosides; Flavonoids; Phenylpropanoids and polyketides; Organic compounds;
Synonyms:  Quercetin 3-rhamnoside
Quercitroside
Quercetrin
Quercimelin
Thujin
Quercetin 3-L-rhamnoside
Quercetin-3-L-rhamnoside
Quercetin 3-O-rhamnoside
Quercitronic acid
......

Chemical structure:
Depiction based on curated SMILES O OH HO OH OH OH OH OH H H H H H 3 C H O O O

Evidence for compound's anti-virulence activity:

Salmonella
Related VFcategory: Effector delivery system
Target: Not determined
Drug effect: Inhibits expression of related genes and effectors in Salmonella T3SS.
Max phase: Preclinical (in vivo)
Publication:
Li Q, et al., 2023. Quercitrin Is a Novel Inhibitor of Salmonella enterica Serovar Typhimurium Type III Secretion System. Molecules 28(14):5455.

Staphylococcus
Related VFcategory: Adherence; Others
Target: SrtA
Drug effect: Inhibits SrtA activity and SrtA-related virulence phenotypes including fibrinogen adhesion.
Max phase: Preclinical (in vitro)
Publication:
Liu B, et al., 2015. Quercitrin, an inhibitor of Sortase A, interferes with the adhesion of Staphylococcal aureus. Molecules 20(4):6533-43.








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