Salmonella
Related VFcategory: Effector delivery system
Target: Not determined
Drug effect: Inhibits expression of related genes and effectors in Salmonella T3SS.
Max phase: Preclinical (in vivo)
Publication: Li Q, et al., 2023. Quercitrin Is a Novel Inhibitor of Salmonella enterica Serovar Typhimurium Type III Secretion System. Molecules 28(14):5455.
Staphylococcus
Related VFcategory: Adherence; Others
Target: SrtA
Drug effect: Inhibits SrtA activity and SrtA-related virulence phenotypes including fibrinogen adhesion.
Max phase: Preclinical (in vitro)
Publication: Liu B, et al., 2015. Quercitrin, an inhibitor of Sortase A, interferes with the adhesion of Staphylococcal aureus. Molecules 20(4):6533-43.