Drug details:
Molecular formula: C₂₁H₂₀O₁₁

Standard name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one

Synonyms:

Lutexin Luteolin-8-glucoside Luteolin 8-C-glucoside Orientin (Flavone) Luteolin 8-glucoside Orientine 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy- 8-beta-D-glucosylluteolin Luteolin-8-C-glucoside ......

Curated SMILES: C1=CC(=C(C=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)O)O

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VFcategory: Others
Target: SrtA
Drug effect: Inhibits SrtA activity and SrtA-related virulence phenotypes including the adherence, biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Wang L, et al., 2021. Orientin mediates protection against MRSA-induced pneumonia by inhibiting Sortase A. Virulence 12(1):2149-2161.