Drug details:
Molecular formula: C₁₆H₂₆O₃

Standard name: 1-[(1R,2R,4aR,6S,8aS)-2-hydroxy-1,2,6-trimethyl-4a,5,6,7,8,8a-hexahydronaphthalen-1-yl]-3-hydroxypropan-1-one

Synonyms:

(+)-Aspermytin A 1-[(1R,2R,4aR,6S,8aS)-2-hydroxy-1,2,6-trimethyl-4a,5,6,7,8,8a-hexahydronaphthalen-1-yl]-3-hydroxypropan-1-one

Curated SMILES: C[C@H]1CC[C@H]2[C@H](C1)C=C[C@@]([C@]2(C)C(=O)CCO)(C)O

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VF: FnBPs (Fibronectin binding proteins)
Target: SrtA
Drug effect: Inhibits SrtA-mediated S. aureus adhesion to fibronectin.
Max phase: Preclinical (in vitro)
Publication:
Park SC, et al., 2020. Sortase A-Inhibitory Metabolites from a Marine-Derived Fungus Aspergillus sp. Mar Drugs 18(7):359.