Home
Search
Category
Compounds
Status
Download
Contacts
Resources



Erianin

Drug details:
Molecular formula: C18H22O5

Classification: Stilbenes; Phenylpropanoids and polyketides; Organic compounds;
Synonyms:  2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol
2-methoxy-5-(3,4,5-trimethoxyphenethyl)phenol
2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-phenol
Phenol, 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]-
Erianin?
2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol
Dendrobium chrysotoxum
B817373-K388, same as
Erianin2-methoxy-5-(3,4,5-trimethoxyphenethyl)phenol
2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-phenol

Chemical structure:
Depiction based on curated SMILES OH CH 3 O CH 3 O CH 3 O CH 3 O

Evidence for compound's anti-virulence activity:

Staphylococcus
Related VF: FnBPs (Fibronectin binding proteins)
Target: SrtA
Drug effect: Inhibits SrtA-mediated S. aureus adhesion to fibronectin and biofilm formation.
Max phase: Preclinical (in vivo)
Publication:
Ouyang P, et al., 2018. Erianin against Staphylococcus aureus Infection via Inhibiting Sortase A. Toxins (Basel) 10(10):385.








Back to Top
Back to Top
2004-2024 NIPB, CAMS&PUMC