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Compound category: 2-arylbenzofuran flavonoids
(total 17 related compounds in database, current show from 1 to 10)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
(-)-Hopeaphenol Depiction based on curated SMILES HO O OH HO HO OH OH O HO HO OH OH Pseudomonas
Yersinia
TTSS (Type III secretion system)
TTSS (Type III secretion system)
Preclinical (in vivo)
Preclinical (in vivo)
Zetterström CE, et al. 2013. PLoS One
3-[1-[3-(1,3-benzothiazol-2-ylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES O HO HO N N N H N S N O O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[3-(9H-fluoren-9-ylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N N O N H N O OH O HO Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[3-(benzhydrylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N N O NH N O OH O HO Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[3-(benzylamino)-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N O HO HO N NH N O O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[3-[(1-benzylpiperidin-4-yl)amino]-3-oxopropyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES O OH OH N N NH O N N O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[5-(9H-fluoren-9-ylamino)-5-oxopentyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N O NH N O OH O HO N Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[5-(benzylamino)-5-oxopentyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES N O OH OH N HN N O O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[5-(cyclopropylamino)-5-oxopentyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES HO O HO O N N NH N O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
3-[1-[5-[(1-benzylpiperidin-4-yl)amino]-5-oxopentyl]triazol-4-yl]-6-hydroxy-2-phenyl-1-benzofuran-5-carboxylic acid Depiction based on curated SMILES O OH OH N N HN N N O O Yersinia TTSS secreted effectors Preclinical (in vitro) Huang Z, et al. 2010. Chem Biol Drug Des
   


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