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Compound category: Indoles
(total 74 related compounds in database, current show from 31 to 40)
 
Compound name 2D structure Target pathogen(s) Related VF/VFcategory Max phase Reference(s)
methyl (1S,12S)-16-[(4,6-dichloro-2H-chromen-3-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES Cl O Cl N H O O H CH 3 H O N Mycobacterium Exoenzyme Preclinical (in vitro) Nören-Müller A, et al. 2008. Angew Chem Int Ed Engl
methyl (1S,12S)-16-[(4-chloro-6-fluoro-2H-chromen-3-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES F O Cl N H O O H CH 3 H O N Mycobacterium Exoenzyme Preclinical (in vitro) Nören-Müller A, et al. 2008. Angew Chem Int Ed Engl
methyl (1S,12S)-16-[(5-chloro-1H-indol-3-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES Cl N H N H O O H CH 3 H O N Mycobacterium Exoenzyme Preclinical (in vitro) Nören-Müller A, et al. 2008. Angew Chem Int Ed Engl
methyl (1S,12S)-16-[(5-methylfuran-2-yl)methyl]-13-oxo-3,16-diazatetracyclo[10.3.1.02,10.04,9]hexadeca-2(10),4,6,8-tetraene-14-carboxylate Depiction based on curated SMILES H CH 3 O O NH CH 3 O H N O Mycobacterium Exoenzyme Preclinical (in vitro) Nören-Müller A, et al. 2008. Angew Chem Int Ed Engl
Compound 4a
(internal name in literature)		 Depiction based on curated SMILES N N H Br N N H Mycobacterium Biofilm Preclinical (in vitro) Zeiler MJ, et al. 2020. ChemMedChem
Compound 4b
(internal name in literature)		 Depiction based on curated SMILES N Br HN Cl N NH Mycobacterium Biofilm Preclinical (in vitro) Zeiler MJ, et al. 2020. ChemMedChem
Compound 4c
(internal name in literature)		 Depiction based on curated SMILES N Br HN F N NH Mycobacterium Biofilm Preclinical (in vitro) Zeiler MJ, et al. 2020. ChemMedChem
Compound 4d
(internal name in literature)		 Depiction based on curated SMILES N Br HN CH 3 N NH Mycobacterium Biofilm Preclinical (in vitro) Zeiler MJ, et al. 2020. ChemMedChem
Compound 4e
(internal name in literature)		 Depiction based on curated SMILES N Br HN CH 3 N NH O Mycobacterium Biofilm Preclinical (in vitro) Zeiler MJ, et al. 2020. ChemMedChem
Compound 4f
(internal name in literature)		 Depiction based on curated SMILES N Br HN NH 2 N NH Mycobacterium Biofilm Preclinical (in vitro) Zeiler MJ, et al. 2020. ChemMedChem
   


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